Wedgefield is an unincorporated community and census designated place (CDP) in the High Hills of Santee area in western Sumter County, South Carolina, United States. Wedgefield is also a Census Designated Place (CDP). Wedgefield was so named because its location was likened to a "wedge" into the High Hills of Santee. In the 18th and 19th centuries it was the location of many plantations, notably those of the Singleton family, which produced First Lady of the United States, Angelica Singleton Van Buren. Today the plantations are gone except for their cemeteries and Wedgefield is today noted as the location of a state park, a state forest and other recreational places. When the railroad came through in the 19th century, the commercial center of Wedgefield developed at the intersection of the railroad, Kings Highway and Wedgefield Road. It has its own post office with the Zip Code of 29168.